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pentobarbital will lessen the level or result of clozapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will lower the extent or outcome of donepezil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Significance Unidentified.pentobarbital will decrease the level or impact of me